NAD+ — 1000mg

Description

NAD+ at 1000mg represents a full protocol vial for women running sustained NAD+ repletion therapy. At this scale, the focus shifts from acute repletion to maintenance of elevated NAD+ pools — keeping sirtuin enzymes active, PARP repair machinery functional, and mitochondrial NAD+/NADH ratios optimized for energy production. Research on sustained NAD+ elevation shows cumulative benefits: improved DNA repair capacity, enhanced mitochondrial biogenesis over 8–12 weeks, and in some studies, measurable improvements in muscle strength and cognitive function.

For perimenopausal and post-menopausal women, sustained NAD+ repletion is increasingly recognized as a meaningful component of longevity medicine — addressing the mitochondrial dysfunction, cognitive changes, and fatigue that accompany the hormonal transition. It also synergizes with sirtuin activators (resveratrol, pterostilbene) and mitochondrial support peptides like SS-31 and MOTS-c for comprehensive cellular health protocols.

Female-calibrated dosing: 50mg subcutaneous daily, or 100–250mg IV 1–2x per week. The 1000mg vial supports 10–20 IV sessions at standard doses, or approximately 4–8 weeks of daily subcutaneous dosing.

Storage: Store lyophilized powder below -20°C. After reconstitution, refrigerate at 2–8°C and use within 14 days. Minimize air exposure — NAD+ is sensitive to oxidation.