DSIP (Delta Sleep-Inducing Peptide) — 5mg

Description

Delta sleep-inducing peptide (DSIP) is a neuropeptide isolated from rabbit cerebral venous blood that promotes delta-wave (slow-wave) sleep — the deepest, most physiologically restorative phase of the sleep cycle. Its mechanism is hypothalamic: it modulates the sleep-wake regulatory centers to increase delta-wave amplitude without causing sedation, which means it restores sleep architecture rather than forcing unconsciousness. Delta sleep is when growth hormone is pulsed, when short-term memories consolidate into long-term storage, and when cellular autophagy and repair mechanisms are most active.

For women, sleep disruption in perimenopause is rarely about inability to fall asleep — it’s about inability to maintain deep sleep and waking repeatedly in the second half of the night (when cortisol begins rising). DSIP addresses the delta wave architecture that tends to collapse during hormonal transitions. It also has demonstrated effects on cortisol normalization, stress axis modulation, and pain threshold — making it relevant for women with cyclical insomnia, high nighttime cortisol, or pain-disrupted sleep.

Female-calibrated dosing: 100–200mcg subcutaneously at bedtime, 3–5x/week. Effects are cumulative — most women notice improved sleep architecture by week 2. Run 4–6 week cycles. Can be combined with Pinealon for comprehensive circadian support.

Storage: Store lyophilized powder below -20°C. After reconstitution, refrigerate at 2–8°C and use within 30 days.